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Three selected LabEx IGO projects were awarded 300 k€ each - Labex IGO
Three selected LabEx IGO projects were awarded 300 k€ each - Labex IGO

IJMS | Free Full-Text | NK Cell Hyporesponsiveness: More Is Not Always  Better
IJMS | Free Full-Text | NK Cell Hyporesponsiveness: More Is Not Always Better

Natural, Proteolytic Release of a Soluble Form of Human IL-15 Receptor  α-Chain That Behaves as a Specific, High Affinity IL-15 Antagonist | The  Journal of Immunology
Natural, Proteolytic Release of a Soluble Form of Human IL-15 Receptor α-Chain That Behaves as a Specific, High Affinity IL-15 Antagonist | The Journal of Immunology

Molecules | Free Full-Text | Mechanistic and Structural Insights on the  IL-15 System through Molecular Dynamics Simulations
Molecules | Free Full-Text | Mechanistic and Structural Insights on the IL-15 System through Molecular Dynamics Simulations

Soluble Interleukin-15 Receptor α (IL-15Rα)-sushi as a Selective and Potent  Agonist of IL-15 Action through IL-15Rβ/γ: HYPERAGONIST IL-15·IL-15Rα  FUSION PROTEINS - ScienceDirect
Soluble Interleukin-15 Receptor α (IL-15Rα)-sushi as a Selective and Potent Agonist of IL-15 Action through IL-15Rβ/γ: HYPERAGONIST IL-15·IL-15Rα FUSION PROTEINS - ScienceDirect

Frontiers | Single-Chain Soluble Receptor Fusion Proteins as Versatile  Cytokine Inhibitors | Immunology
Frontiers | Single-Chain Soluble Receptor Fusion Proteins as Versatile Cytokine Inhibitors | Immunology

Research - mocka
Research - mocka

Erwan MORTIER | Research Director CNRS | PhD | University of Nantes, Nantes  | UNIV Nantes | Centre de recherche en cancérologie Nantes angers (CRCNA)
Erwan MORTIER | Research Director CNRS | PhD | University of Nantes, Nantes | UNIV Nantes | Centre de recherche en cancérologie Nantes angers (CRCNA)

Soluble Interleukin-15 Receptor α (IL-15Rα)-sushi as a Selective and Potent  Agonist of IL-15 Action through IL-15Rβ/γ: HYPERAGONIST IL-15·IL-15Rα  FUSION PROTEINS - ScienceDirect
Soluble Interleukin-15 Receptor α (IL-15Rα)-sushi as a Selective and Potent Agonist of IL-15 Action through IL-15Rβ/γ: HYPERAGONIST IL-15·IL-15Rα FUSION PROTEINS - ScienceDirect

Loop | Erwan Mortier
Loop | Erwan Mortier

Frontiers | Bone Marrow Lymphoid Niche Adaptation to Mature B Cell  Neoplasms | Immunology
Frontiers | Bone Marrow Lymphoid Niche Adaptation to Mature B Cell Neoplasms | Immunology

People - mocka
People - mocka

Frontiers | IL-15 in the Combination Immunotherapy of Cancer | Immunology
Frontiers | IL-15 in the Combination Immunotherapy of Cancer | Immunology

Rational modification, synthesis and biological evaluation of N-substituted  phthalazinone derivatives designed to target interleukine-15 protein -  ScienceDirect
Rational modification, synthesis and biological evaluation of N-substituted phthalazinone derivatives designed to target interleukine-15 protein - ScienceDirect

Pièce - Galerie kreo
Pièce - Galerie kreo

Discovery of a Small-Molecule Inhibitor of Interleukin 15:  Pharmacophore-Based Virtual Screening and Hit Optimization | Journal of  Medicinal Chemistry
Discovery of a Small-Molecule Inhibitor of Interleukin 15: Pharmacophore-Based Virtual Screening and Hit Optimization | Journal of Medicinal Chemistry

Interleukin-15 and Its Soluble Receptor Mediate the Response to Infliximab  in Patients With Crohn's Disease - Gastroenterology
Interleukin-15 and Its Soluble Receptor Mediate the Response to Infliximab in Patients With Crohn's Disease - Gastroenterology

Interleukin-15 Plays a Central Role in Human Kidney Physiology and Cancer  through the γc Signaling Pathway | PLOS ONE
Interleukin-15 Plays a Central Role in Human Kidney Physiology and Cancer through the γc Signaling Pathway | PLOS ONE

Erwan MORTIER | Research Director CNRS | PhD | University of Nantes, Nantes  | UNIV Nantes | Centre de recherche en cancérologie Nantes angers (CRCNA)
Erwan MORTIER | Research Director CNRS | PhD | University of Nantes, Nantes | UNIV Nantes | Centre de recherche en cancérologie Nantes angers (CRCNA)

Emergence of NK Cell Hyporesponsiveness after Two IL-15 Stimulation Cycles  | The Journal of Immunology
Emergence of NK Cell Hyporesponsiveness after Two IL-15 Stimulation Cycles | The Journal of Immunology

Soluble Interleukin-15 Receptor α (IL-15Rα)-sushi as a Selective and Potent  Agonist of IL-15 Action through IL-15Rβ/γ - Journal of Biological Chemistry
Soluble Interleukin-15 Receptor α (IL-15Rα)-sushi as a Selective and Potent Agonist of IL-15 Action through IL-15Rβ/γ - Journal of Biological Chemistry

Role of IL-15Rα shedding in trans-presentation | PNAS
Role of IL-15Rα shedding in trans-presentation | PNAS

Frontiers | Modulating Cytokine Production via Select Packaging and  Secretion From Extracellular Vesicles | Immunology
Frontiers | Modulating Cytokine Production via Select Packaging and Secretion From Extracellular Vesicles | Immunology

Erwan MORTIER | Research Director CNRS | PhD | University of Nantes, Nantes  | UNIV Nantes | Centre de recherche en cancérologie Nantes angers (CRCNA)
Erwan MORTIER | Research Director CNRS | PhD | University of Nantes, Nantes | UNIV Nantes | Centre de recherche en cancérologie Nantes angers (CRCNA)

Natural, Proteolytic Release of a Soluble Form of Human IL-15 Receptor  α-Chain That Behaves as a Specific, High Affinity IL-15 Antagonist | The  Journal of Immunology
Natural, Proteolytic Release of a Soluble Form of Human IL-15 Receptor α-Chain That Behaves as a Specific, High Affinity IL-15 Antagonist | The Journal of Immunology

News - mocka
News - mocka

Ronan Bouroullec | SUSPENSION 'LIANE' À TROIS LUMIÈRES, GRANDE VARIANTE,  ÉDITION GALERIE KREO (2010) | MutualArt
Ronan Bouroullec | SUSPENSION 'LIANE' À TROIS LUMIÈRES, GRANDE VARIANTE, ÉDITION GALERIE KREO (2010) | MutualArt

Erwan MORTIER | Research Director CNRS | PhD | University of Nantes, Nantes  | UNIV Nantes | Centre de recherche en cancérologie Nantes angers (CRCNA)
Erwan MORTIER | Research Director CNRS | PhD | University of Nantes, Nantes | UNIV Nantes | Centre de recherche en cancérologie Nantes angers (CRCNA)

Erwan MORTIER | Research Director CNRS | PhD | University of Nantes, Nantes  | UNIV Nantes | Centre de recherche en cancérologie Nantes angers (CRCNA)
Erwan MORTIER | Research Director CNRS | PhD | University of Nantes, Nantes | UNIV Nantes | Centre de recherche en cancérologie Nantes angers (CRCNA)

Emergence of NK Cell Hyporesponsiveness after Two IL-15 Stimulation Cycles  | The Journal of Immunology
Emergence of NK Cell Hyporesponsiveness after Two IL-15 Stimulation Cycles | The Journal of Immunology